UNC9815
UNC9815 is a D1 dopamine receptor (D1R) orthosteric allosteric modulator (PAM) . UNC9815 can dose-dependently enhance the functional efficacy of dopamine in β-inhibitory protein recruitment experiments and cAMP accumulation experiments. When used in combination with other PAMs, UNC9815 exhibits a significant synergistic enhancement effect. UNC9815 can be used to study neurological and psychiatric diseases such as Parkinson's disease and schizophrenia[1].
Product Specifications
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CC(C)(C1=CC=C2C(SC(NC(C3=CC=NC=C3)=O)=C2C(N)=O)=C1)C
Molecular Formula
C19H19N3O2S
Molecular Weight
353.44
References & Citations
[1]Wang K, et al. Multiple Allosteric Sites Allow for Synergistic Enhancement of GPCR Signaling. bioRxiv [Preprint]. 2025 Oct 22:2025.10.21.683604.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D1 Receptor
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