HJ-4
HJ-4 is a Piperine (HY-N0144) derivative. HJ-4 potently inhibits the proliferation of CRC cells by dose-dependently reducing colony formation and DNA synthesis. HJ-4 markedly suppresses the adhesion, migration, invasion and induces apoptosis of CRC cells. HJ-4 demonstrates anti-tumor efficacy in chicken embryo chorioallantoic membrane (CAM) model implanted with HCT116/SW480 tumor spheroids. HJ-4 can be used for the study of colorectal cancer (CRC) [1].
Product Specifications
CAS Number
[1313741-00-2]
UNSPSC
12352005
Target
Apoptosis; Drug Derivative
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Purity
98.02
Smiles
COC1=CC=CC=C1N2CCN(CC2)C(/C=C/C=C/C3=CC4=C(OCO4)C=C3)=O
Molecular Formula
C23H24N2O4
Molecular Weight
392.45
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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