α-Synuclein-IN-17
α-Synuclein-IN-17 (Compound 10) is an α-Synuclein inhibitor, with an IC50 value of 9 μM. α-Synuclein-IN-17 exhibits potent inhibitory activity against both in-vitro assembled asyn fibrils and LBD brain tissue-amplified asyn fibrils. α-Synuclein-IN-17 can be used for the study of Parkinson's disease (PD) and Lewy Body Disease (LBD) [1].
Product Specifications
CAS Number
[676458-63-2]
UNSPSC
12352005
Target
α-synuclein
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Purity
98
Smiles
COC1=CC(CN2CCN(CC3=CC(OC)=CC=C3OC)CC2)=CC(OC)=C1O
Molecular Formula
C22H30N2O5
Molecular Weight
402.48
References & Citations
[1]Hwang H, et al. Identification of small molecule dimethyoxyphenyl piperazine inhibitors of alpha-synuclein fibril growth. Sci Rep. 2025 Sep 26;15 (1) :33108.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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