Nrf2 activator-22
Nrf2 activator-22, a Nrf2 activator, is a PROTAC target protein ligand (Ligands for Target Protein for PROTAC) . Nrf2 activator-22 can be used for synthesis PROTAC K-Ras Degrader-7 (HY-178873) [1].
Product Specifications
CAS Number
[3082764-64-2]
UNSPSC
12352005
Target
Keap1-Nrf2; Ligands for Target Protein for PROTAC
Related Pathways
NF-κB; PROTAC
Field of Research
Cancer
Smiles
OC1=C2C(N=NN2C)=CC(C(C3=CC(CN4S(=O)(C5=CC=CC=C5O[C@@H](C4)C)=O)=C(C=C3)C)CC(O)=O)=C1
Molecular Formula
C27H28N4O6S
Molecular Weight
536.60
References & Citations
[1]Austin J, et al. PROTAC Compounds Binding Keap1 Ubiquitin Ligase for Targeted Protein Degradation. WO2025085815A1. 2025-04-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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