TGI-15
TGI-15 is a highly selective prostaglandin F receptor antagonist. TGI-15 inhibits downstream signaling pathways by blocking the binding of PGF2 α to FP receptors. TGI-15 can be used for research on fibrotic and inflammatory conditions[1].
Product Specifications
CAS Number
[3073601-32-5]
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
OC(C1(CC2)C=C(C3=CC=CC=C3OC(F)F)C2(NC(C4=C(C=C(Br)C=C5)C5=NC(C6=CC=CC=C6)=C4C)=O)CC1)=O
Molecular Formula
C33H27BrF2N2O4
Molecular Weight
633.48
References & Citations
[1]Liang S H. Novel N-Arylquinoline-4-carboxamide Derivatives as Prostaglandin F Receptor Antagonists[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
FP
Curated Selection
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