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SDH-IN-38

SDH-IN-38 (Compound IIIe) is a Succinate dehydrogenase inhibitor. SDH-IN-38 is an antifungal agent, with an EC50 value of 0.009 μg/mL against R. solani mycelia. SDH-IN-38 inhibits mycelial growth by affecting mycelial respiration. SDH-IN-38 induces cellular senescenc and reduces mitochondrial membrane potential in mycelia[1].

Product Specifications

CAS Number

[3066787-57-0]

UNSPSC

12352005

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CC1=NC(C(F)F)=C(C(NC2=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=CC=C2)=O)S1

Molecular Formula

C19H12ClF5N2O2S

Molecular Weight

462.82

References & Citations

[1]Yan Z, et al. Discovery of Thiazole-5-Carboxamide Derivatives Containing Diphenyl Ether Fragments as Potential Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2025 Oct 22;73 (42) :26529-26539.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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