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BRP-821

BRP-821 is a soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 0.4 nM. BRP-821 can be used for the researches of inflammation, cardiovascular, metabolic and neurological disease [1].

Product Specifications

Product Name Alternative

FP30

UNSPSC

12352005

Target

Epoxide Hydrolase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Smiles

COC1=CC(C(F)(F)F)=C(C=C1)CNC(C2=CC=C3C(N=C(N3C)CC4=CC=C(C=C4)C5(CC5)C(F)F)=C2)=O

Molecular Formula

C29H26F5N3O2

Molecular Weight

543.53

References & Citations

[1]Çalışkan K, et al. Harnessing structure-activity relationships to repurpose the FLAP inhibitor BRP-7 into potent and selective sEH inhibitors. Bioorg Chem. 2025 Oct;165:108997.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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