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Remodelin-C6-COOH

Remodelin-C6-COOH is a synthesized target protein ligand-linker conjugate that can be used for synthesis of NP1192 (HY-178360) . NP1192 is a potent NAT10 PROTAC degrader with anti-tumor activity[1].

Product Specifications

CAS Number

[2966791-35-3]

UNSPSC

12352005

Target

Target Protein Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

N#CC1=CC=C(C=C1)C2=CSC(N(/N=C3CCCC/3)CCCCCCC(O)=O)=N2

Molecular Formula

C22H26N4O2S

Molecular Weight

410.53

References & Citations

[1]Ao, K., et al. Targeted NAT10 Degradation by PROTAC NP1192 Suppresses Hypoxia-Adaptive Glycolysis and Reinvigorates CD8+ Effector T-Cell Function for Synergistic Cancer Immunotherapy. ACS Central Science. 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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