UNC10415667
UNC10415667 is a NSD2 degrader, with a DC50 values of 460 nM. UNC10415667 can be used for the study of cancers driven by NSD2 overexpression or dysregulation, such as multiple myeloma, acute lymphocytic leukemia, and prostate cancer[1].
Product Specifications
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(C1=CC=C(N2)C(OCC2=O)=C1)N(C3CC3)CC4=CC=C(C(NC5=CC6=C(CN(C(C7=CC=C(C=O)C=C7)=O)CC6)C=C5)=O)C=C4
Molecular Formula
C37H32N4O6
Molecular Weight
628.67
References & Citations
[1]Robertson, K. C., Amann, S. J., Liu, T., et al. Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22. bioRxiv. 2025
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NSD2/MMSET/WHSC1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
U1000-94D-PE 200 µL
E2EPF, CT (Ubiquitin-conjugating Enzyme E2S, Ubiquitin-conjugating Enzyme E2-24kD, Ubiquitin-protein Ligase S, Ubiquitin Carrier Protein S, E2-EPF5, Ubiquitin-conjugating Enzyme E2-EPF5, UBE2S, E2EPF, OK/SW-cl.73) (PE) discontinued
Ask
View Details 
MBS2059782-01 0.1 mL
APC/CY7-Linked Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2)
Ask
View Details MBS2059782-02 0.2 mL
APC/CY7-Linked Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2)
Ask
View Details 
MBS2059782-03 0.5 mL
APC/CY7-Linked Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2)
Ask
View Details MBS2059782-04 1 mL
APC/CY7-Linked Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2)
Ask
View Details MBS2059782-05 5 mL
APC/CY7-Linked Polyclonal Antibody to Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2)
Ask
View Details