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DHODH-IN-31

DHODH-IN-31 is a human dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.59 μM. DHODH-IN-31 exhibits antiviral activity. DHODH-IN-31 can be used for the research of infection, such as SARS-CoV-2[1].

Product Specifications

UNSPSC

12352005

Target

Dihydroorotate Dehydrogenase; SARS-CoV

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Purity

99.55

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1NC(NC2=CC(C3=CC=CC=C3)=CC=C2)=NC4=C1C=CC=C4

Molecular Formula

C20H15N3O

Molecular Weight

313.35

References & Citations

[1]Bruna F. Godoi, et al. Quinazolinones as Bioisosteres of Naphthoquinones: A Path to Potent HsDHODH Inhibitors with Optimized Properties. ACS Medicinal Chemistry Letters Article ASAP

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-178156/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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