Antitumor agent-209
Antitumor agent-209 (Compound 10g), a quinolone derivative, is an antitumor agent. Antitumor agent-209 can inhibit proliferation of HCT-116, RKO, DLD1, HepG2, BGC-823, NCI-H1650 and SK-OV-3 cells with IC50 values of 0.37, 0.58, 0.81, 0.79, 0.89, 0.78 and 0.89 μM[1].
Product Specifications
CAS Number
[1616473-67-6]
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
FC(C=C1)=CC=C1COC2=CC=C3C(N=CC=C3NCCN(CC)CC)=C2
Molecular Formula
C22H26FN3O
Molecular Weight
367.46
References & Citations
[1]Li S, et al. Design, synthesis, structure-activity relationships and mechanism of action of new quinoline derivatives as potential antitumor agents. Eur J Med Chem. 2019 Jan 15;162:666-678.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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