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Hsp90-IN-44

Hsp90-IN-44 (compound 16) is a Hsp90 inhibitor with an IC50 of 9.8 µM. Hsp90-IN-44 can be used for cancer research[1].

Product Specifications

CAS Number

[934346-12-0]

UNSPSC

12352005

Target

HSP

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C1N[C@@H](C2=C(C(N3)=CC=CC3=O)C=C(C=C2)F)CC4=NC(N)=NC(C)=C41

Molecular Formula

C19H16FN5O2

Molecular Weight

365.36

References & Citations

[1]McBride CM, et al. Design, structure-activity relationship, and in vivo characterization of the development candidate NVP-HSP990. J Med Chem. 2014 Nov 13;57 (21) :9124-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HSP90

Curated Selection

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