MG-Lin1
MG-Lin1 is a molecular glucose degrading agent that targets the Lin28 protein. MG-Lin1 can significantly reduce the mRNA levels of let-7 targeting oncogenes. MG-Lin1 can significantly inhibit the migration ability of cancer cells. MG-Lin1 has no obvious cytotoxicity. MG-Lin1 can be used for cancer research[1].
Product Specifications
UNSPSC
12352005
Target
MicroRNA; Molecular Glues
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1=NN=C2C=CC(C3=CC=CC(N(C)C(/C=C/C4=CC=C(C=C4)C(F)(F)F)=O)=C3)=NN12
Molecular Formula
C23H18F3N5O
Molecular Weight
437.42
References & Citations
[1]Kashkush A, et al. PROTAC and Molecular Glue Degraders of the Oncogenic RNA Binding Protein Lin28. Macromol Biosci. 2025 Mar;25 (3) :e2400427.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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