T26A
T26A is a competitive prostaglandin transporter (PGT) inhibitor (Ki=378 nM) . T26A is promising for research of prostaglandin signaling and inflammatory diseases (e.g., glaucoma, pulmonary hypertension) [1].
Product Specifications
CAS Number
[958860-12-3]
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
O=C(NCCOCCOCCN=[N+]=[N-])C1=CC=C(NC2=NC(NCCOCCOCCNC(C3=CC=CC=C3)=O)=NC(NC4=CC=C(O)C=C4)=N2)C=C1
Molecular Formula
C35H43N11O7
Molecular Weight
729.79
References & Citations
[1]Chi Y, et al. Development of a high-affinity inhibitor of the prostaglandin transporter. J Pharmacol Exp Ther. 2011 Nov;339 (2) :633-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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