Kinase modulator-1
Kinase modulator-1 (P142, MS: m/z445) is a kinase modulator. Kinase modulator-1 can inhibit Bcr-Abl activity, especially against drug-resistant mutant kinases (such as T315I Bcr-Abl) . Kinase modulator-1 can be used for cancers like chronic myelogenous leukemia (CML) research[1].
Product Specifications
CAS Number
[927697-17-4]
UNSPSC
12352005
Target
Bcr-Abl
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NC1=C(C(N(C)C)=O)C=C(C2=CN=C3NC=C(C3=C2)C4=C(OC)C=CC=C4)C=C1)OC
Molecular Formula
C25H24N4O4
Molecular Weight
444.48
References & Citations
[1]Arnold W D, et al. Pyrrolo-pyridine kinase modulators. US20070043068A1. 2007-02-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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