PHD2-IN-6
PHD2-IN-6 (Example 89) is a HIF prolyl hydroxylase 2 (PHD2) inhibitor with an IC50 of 31.6 nM. PHD2-IN-6 stimulates encoding erythropoietin (EPO) production. PHD2-IN-6 can be used for inflammatory diseases like inflammatory bowel disease (IBD) and rheumatoid arthritis research[1].
Product Specifications
CAS Number
[1193382-79-4]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CN(C2=NC3=C(N2)C=C(S(=O)(C4=CC=CC=C4)=O)C(Cl)=C3)N=C1)O
Molecular Formula
C17H11ClN4O4S
Molecular Weight
402.81
References & Citations
[1]Hocutt F M, et al. Benzoimidazoles as prolyl hydroxylase inhibitors. WO2009134750A1. 2009-11-05.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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