Sonvuterkib

Sonvuterkib (WX001) is a potent and orally active extracellular signal-regulated kinases (ERK) inhibitor with IC50 values of 1.4, 0.54 nM for ERK1, ERK2, respectively. Sonvuterkib inhibits cell proliferation. Sonvuterkib shows anticancer activity[1][2].

Product Specifications

CAS Number

[2890225-50-8]

Product Name Alternative

WX001

UNSPSC

12352005

Target

ERK

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Field of Research

Cancer

Smiles

O=C1C2=C(C3(COC3)N1CC4=NC(C)=CC=C4)SC(C5=C(C)C=NC(NC6=CC=NN6C)=N5)=N2

Molecular Formula

C23H22N8O2S

Molecular Weight

474.54

References & Citations

[1]Ii, Yi, et al. Thiazole-lactam-spiroheterocyclic compounds and applications thereof. WO2023274256A1.|[2]WHO Drug Information. International Nonproprietary Names for Pharmaceutical.