Ledasorexton
Ledasorexton (Example 1) is an orally active OX2R agonist (EC50: 0.99 nM) . Ledasorexton has awakening effect[1].
Product Specifications
CAS Number
[2758363-88-9]
UNSPSC
12352005
Target
Orexin Receptor (OX Receptor)
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
NC([C@@H](C1CC1)N2[C@@]3([H])C[C@]([C@]4([H])[C@@H](CN(C5=NC=C(F)C=N5)CC4)OC)([H])C[C@]2([H])CC3)=O
Molecular Formula
C22H32FN5O2
Molecular Weight
417.52
References & Citations
[1]YOSHIDA Yu, et al. Substituted piperidine compound and application thereof. Patent. WO2022014680 A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
OX1 Receptor; OX2 Receptor
Curated Selection
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