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Izicopan

Izicopan (INF056) is a complement factor C5a receptor antagonist. Izicopan inhibits C5a-induced calcium mobilization with an IC50 of 10-100 nM[1].

Product Specifications

CAS Number

[2489430-53-5]

Product Name Alternative

INF056

UNSPSC

12352005

Target

Complement System

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

O=C(C1=C(C=CC=C1F)F)N2[C@@H](C3=CC=C(C=C3)NC4CCCC4)[C@H](C[C@H](C2)C(F)(F)F)C(NC5=CC(C(F)(F)F)=C(C=C5)C)=O

Molecular Formula

C33H31F8N3O2

Molecular Weight

653.61

References & Citations

[1]Yong Li, et al. Fused piperidinyl bicyclic and related compounds as modulators of c5a receptor. Patent. WO2020182384

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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