Izicopan
Izicopan (INF056) is a complement factor C5a receptor antagonist. Izicopan inhibits C5a-induced calcium mobilization with an IC50 of 10-100 nM[1].
Product Specifications
CAS Number
[2489430-53-5]
Product Name Alternative
INF056
UNSPSC
12352005
Target
Complement System
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=C(C=CC=C1F)F)N2[C@@H](C3=CC=C(C=C3)NC4CCCC4)[C@H](C[C@H](C2)C(F)(F)F)C(NC5=CC(C(F)(F)F)=C(C=C5)C)=O
Molecular Formula
C33H31F8N3O2
Molecular Weight
653.61
References & Citations
[1]Yong Li, et al. Fused piperidinyl bicyclic and related compounds as modulators of c5a receptor. Patent. WO2020182384
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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