CHK1-IN-13

CHK1-IN-13 (Compound 38) is a checkpoint kinase 1 (Chk1) inhibitor with an IC50 of 10-50 nM. CHK1-IN-13 has anticancer activity, and can be used for the research of cancers, such as breast, ovarian and prostate cancer[1].

Product Specifications

CAS Number

[2120398-52-7]

UNSPSC

12352005

Target

Checkpoint Kinase (Chk)

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C(OCC)NCCCOC1=CC(F)=CC(OC)=C1C2=NNC(NC3=NC=C(C#N)N=C3)=C2

Molecular Formula

C21H22FN7O4

Molecular Weight

455.44

References & Citations

[1]Xiong C, et al. 3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (chk1) inhibitors, and their preparations and applications. WO2017132928A1. 2017-08-10.