CHK1-IN-13
CHK1-IN-13 (Compound 38) is a checkpoint kinase 1 (Chk1) inhibitor with an IC50 of 10-50 nM. CHK1-IN-13 has anticancer activity, and can be used for the research of cancers, such as breast, ovarian and prostate cancer[1].
Product Specifications
CAS Number
[2120398-52-7]
UNSPSC
12352005
Target
Checkpoint Kinase (Chk)
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(OCC)NCCCOC1=CC(F)=CC(OC)=C1C2=NNC(NC3=NC=C(C#N)N=C3)=C2
Molecular Formula
C21H22FN7O4
Molecular Weight
455.44
References & Citations
[1]Xiong C, et al. 3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (chk1) inhibitors, and their preparations and applications. WO2017132928A1. 2017-08-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Chk1
Curated Selection
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