EIF4A-IN-2
EIF4A-IN-2 (Compound 93) is an Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-2 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[3083974-69-7]
UNSPSC
12352005
Target
ADC Payload; Eukaryotic Initiation Factor (eIF)
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O[C@]12[C@](OC3=CC(C4=NC=CO4)=CC(OC)=C32)(C5=CC=C(C=C5)OC)[C@H](C6=CC(N)=CC=C6)C[C@@H]1CNC(CN(C)C)=O
Molecular Formula
C33H36N4O6
Molecular Weight
584.66
References & Citations
[1]Li B, et al. Conjugate of protein translation inhibitor and use thereof. WO2025153015A2. 2025-07-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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