PAD-PF2
PAD-PF2 is a PAD4 inhibitor with a Kd of 2.82 µM. PAD-PF2 inhibits Ionomycin (HY-13434) induced protein citrullination in human isolated neutrophils[1].
Product Specifications
UNSPSC
12352005
Target
Protein Arginine Deiminase
Related Pathways
Epigenetics
Field of Research
Inflammation/Immunology
Smiles
O=C(N1CCCC1)[C@@H](N)C2CCN(C3=NC=CC4=C3C=CC=C4C5=NC=C(Cl)C=C5Cl)CC2
Molecular Formula
C25H27Cl2N5O
Molecular Weight
484.42
References & Citations
[1]Dakin LA, et al. Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca2+ dependent allosteric binding site. Nat Commun. 2025 May 16;16 (1) :4579.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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