Z-MAL
Z-MAL is a highly efficient and broad-spectrum HDAC substrate. Z-MAL exhibits high conversion activity for class I, II histone deacetylases, and class III SIRT1. Z-MAL can be used in studies on the structure-activity relationship, subtype selectivity, and inhibitor screening of HDAC[1].
Product Specifications
CAS Number
[642463-22-7]
UNSPSC
12352211
Target
HDAC; Sirtuin
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Others
Smiles
CC(C1=CC=C(NC([C@H](CCCCNC(C)=O)NC(OCC2=CC=CC=C2)=O)=O)C=C1O3)=CC3=O
Molecular Formula
C26H29N3O6
Molecular Weight
479.52
References & Citations
[1]Heltweg B, et al. Subtype selective substrates for histone deacetylases. J Med Chem. 2004 Oct 7;47 (21) :5235-43.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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