PKA-IN-2
PKA-IN-2 (Compound j1) is a serine/threonine kinase J-PKAcα-targeting inhibitor with an IC50 of 6.3 nM. PKA-IN-2 can be used for liver cancer like fibrolamellar hepatocellular carcinoma research[1].
Product Specifications
UNSPSC
12352005
Target
PKA
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer
Smiles
N1(C2=NC=NC=C2)CCSC(C3=C4C(NC=C4)=NC=C3)=C1
Molecular Formula
C15H13N5S
Molecular Weight
295.36
References & Citations
[1]Du L, et al. Chemical Evolution of Aplithianine Class of Serine/Threonine Kinase Inhibitors. J Med Chem. 2025 Jun 26;68 (12) :12756-12785.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PKACα
Curated Selection
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