PHD2-IN-5
PHD2-IN-5 (compound 22) is a potent PHD2 inhibitor with an IC50 of 0.82 μM. PHD2-IN-5 can be used in the study of renal anemia[1].
Product Specifications
CAS Number
[1262131-72-5]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
OC1=C(C(NCC(O)=O)=O)C2=NC=NN2C=C1.Cl
Molecular Formula
C9H9ClN4O4
Molecular Weight
272.65
References & Citations
[1]Ogoshi Y, et al. Lead Generation for a HIF Prolyl Hydroxylase Inhibitor: Discovery of (7-Hydroxy-[1, 2, 4] triazolo [1, 5-a] pyridine-8-carbonyl) glycine as a Lead Compound of Enarodustat[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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