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AChE-IN-87

AChE-IN-87 (Compound 8j) is an AChE inhibitor (IC50: 0.05 μM; Ki: 16.93 nM) . AChE-IN-87 is non-cytotoxic to 3T3 cells. AChE-IN-87 can be used in the study of Alzheimer's disease (AD) [1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

CC(O[C@@H]1[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)O[C@H]1N(/C(SC2)=N/C3=NC4=C(C=C(C(OCCCCCCCC)=O)C=C4)S3)C2=O)=O

Molecular Formula

C32H39N3O12S2

Molecular Weight

721.79

References & Citations

[1]Thanh N D, et al. d-Glucose-Conjugated Benzo [d] thiazole–thiazolidin-4-one Hybrids: Design and Synthesis as Multitarget Anti-Alzheimer Compounds[J]. ACS Medicinal Chemistry Letters, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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