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Adamantan-C-amide-PEG2-C2-amine

Adamantan-C-amide-PEG2-C2-amine (Compound 8) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC β-NF-JQ1 (HY-130256) [1].

Product Specifications

CAS Number

[1577212-91-9]

UNSPSC

12352211

Target

PROTAC Linkers

Related Pathways

PROTAC

Field of Research

Others

Smiles

O=C(NCCOCCOCCN)CC1(C[C@@H](C2)C3)C[C@@H]3C[C@@H]2C1

Molecular Formula

C18H32N2O3

Molecular Weight

324.46

References & Citations

[1]Shoda T, et al. Targeted Protein Degradation by Chimeric Compounds using Hydrophobic E3 Ligands and Adamantane Moiety. Pharmaceuticals (Basel) . 2020 Feb 25;13 (3) :34.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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