PPARγ modulator-3
PPARγ modulator-3 (Compound 11) is a peroxisome proliferator-activated receptor γ (PPARγ) modulator with a KD value of 186 nM. PPARγ modulator-3 is promising for research of insulin resistance (IR) -related diseases, such as type 2 diabetes mellitus (T2DM) and metabolic syndrome[1].
Product Specifications
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
O=C(O)COC1=CC=CC(C(C(C2=CC=C(Br)C=C2)=C3O)OC3=O)=C1
Molecular Formula
C18H13BrO6
Molecular Weight
405.20
References & Citations
[1]Cazzaniga G, et al. Enhancing the Activity of γ-Hydroxy Lactone Derivatives as Innovative Peroxisome Proliferator-Activated Receptor γ Non-Agonists Inhibiting Cyclin-Dependent Kinase 5-Mediated Phosphorylation[J]. European Journal of Medicinal Chemistry, 2025: 117657.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
