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EMD-C02602

EMD-C02602 is a GCN2-targeting agent with IC50 values of 0.023 μM, 4.52 μM, > 10 μM and 0.048 μM for GCN2, PERK, HRland PKR, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Eukaryotic Initiation Factor (eIF)

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=S(NC[C@@H]1CN(C2=NC=NC(C3=CN=C4C=CC(C(F)F)=NN43)=C2)C[C@H](C)C1(F)F)(C)=O

Molecular Formula

C19H21F4N7O2S

Molecular Weight

487.47

References & Citations

[1]Tameire F, et al. In Vivo Tumor Growth Control by General Control Nonderepressible 2-Targeting Agents Results from Kinase Activation. Mol Cancer Ther. 2025 Sep 5:OF1-OF13.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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