Mtb-IN-13

Mtb-IN-13 (Compound 5f) is an inhibitor of Mycobacterium tuberculosis (Mtb), with a MIC of 0.25 μg/mL. The Ki values of MTTB-in-13 for MtCA1, MtCA2, MtC, and 3 are 0.6023, 0.0780, and 0.1994 μM, respectively. Mtb-IN-13 can be used in the research of tuberculosis[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial; Carbonic Anhydrase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=S(C1=CC=C(N2N=NC(COC3=CC4=C(N(C)C(C)=C4C(/C=C/C5=C(Cl)C=CC=C5Cl)=O)C=C3)=C2)C=C1)(N)=O

Molecular Formula

C28H23Cl2N5O4S

Molecular Weight

596.48

References & Citations

[1]Singampalli A, et al. Exploring Indole-Linked Triazole Sulfonamide Derivatives as Potent Mycobacterial Carbonic Anhydrase Inhibitors: Leveraging a Tail Approach for the Design, Synthesis, and In Silico Studies─An In-Depth Multidisciplinary Study. J Med Chem. 2025 Sep 11;68 (17) :18370-18388.