Scr-IN-2
Scr-IN-2 is an effective c-Scr inhibitor with an IC50 of 302 nM. Scr-IN-2 exhibits nanomolar-level anti-breast cancer activity. Scr-IN-2 increases the level of ROS in cells, induces mitochondrial damage, G1 phase arrest, and apoptosis. Scr-IN-2 can be used in the research of breast cancer[1].
Product Specifications
CAS Number
[2787582-78-7]
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS) ; Src
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CCCCN1C(NC(C)(C)C)=NC2=CC=CC=C2C1C3=NN=NN3C(C)(C)C
Molecular Formula
C21H33N7
Molecular Weight
383.53
References & Citations
[1]Zou L, et al. Design and synthesis of tetrazole tethered quinazoline derivatives via azide-isocyanide cross-coupling reaction: Exploring the utility as anticancer agents via the SRC kinase inhibition in breast cancer. Bioorg Chem. 2025 Sep;164:108844.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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