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CB2R ligand-1

CB2R ligand-1 (Compound L14) is a selective Cannabinoid type 2 receptor (CB2R) ligand with a with Ki of 0.16 nM for CB2R over CB1R. CB2R ligand-1 as be used as a tracer for positron emission tomography (PET) imaging of neurodegenerative diseases, inflammation and cancer[1].

Product Specifications

CAS Number

[2816933-22-7]

UNSPSC

12352100

Target

Cannabinoid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Smiles

COCCN1C2=CC=C(C=C2S/C1=N\C(C3C(C)(C3(C)C)C)=O)OC

Molecular Formula

C19H26N2O3S

Molecular Weight

362.49

References & Citations

[1]Ueberham L, et al. Development of Carborane-Based Benzothiazole Analogues as Cannabinoid Receptor Type 2 (CB2R) Ligands. ACS Omega. 2025 Aug 13;10 (33) :38264-38271.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-175730/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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