CB2R ligand-1
CB2R ligand-1 (Compound L14) is a selective Cannabinoid type 2 receptor (CB2R) ligand with a with Ki of 0.16 nM for CB2R over CB1R. CB2R ligand-1 as be used as a tracer for positron emission tomography (PET) imaging of neurodegenerative diseases, inflammation and cancer[1].
Product Specifications
CAS Number
[2816933-22-7]
UNSPSC
12352100
Target
Cannabinoid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Smiles
COCCN1C2=CC=C(C=C2S/C1=N\C(C3C(C)(C3(C)C)C)=O)OC
Molecular Formula
C19H26N2O3S
Molecular Weight
362.49
References & Citations
[1]Ueberham L, et al. Development of Carborane-Based Benzothiazole Analogues as Cannabinoid Receptor Type 2 (CB2R) Ligands. ACS Omega. 2025 Aug 13;10 (33) :38264-38271.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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