LC3 liagnd-2
LC3 liagnd-2 is an E3 ligase ligand. LC3 liagnd-2 can be used for synthesis of PROTAC PDEδ autophagic degrader 1 (HY-157458) [1].
Product Specifications
CAS Number
[2839637-57-7]
UNSPSC
12352100
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Smiles
O=C(O)COC1=C(Br)C=C(/C=C2C(NC3=C\2C=C(I)C=C3)=O)C=C1Br
Molecular Formula
C17H10Br2INO4
Molecular Weight
578.98
References & Citations
[1]Bao J, et al. Discovery of Novel PDEδ Autophagic Degraders: A Case Study of Autophagy-Tethering Compound (ATTEC) . ACS Med Chem Lett. 2023 Dec 29;15 (1) :29-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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