DOPE-C8

DOPE-C8 (1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8) is a zwitterionic phospholipid derived from DOPE that has been used to generate lipid nanoparticles (LNPs) for in vivo delivery of mRNA[1].

Product Specifications

CAS Number

[3081750-70-8]

Product Name Alternative

1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8

UNSPSC

12352211

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Smiles

CCCCCCCCOC(CCNCCOP(OC[C@@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)(O)=O)=O

Molecular Formula

C52H98NO10P

Molecular Weight

928.31

References & Citations

[1]Iwakawa K, et al. Cubic Phase-Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA. Adv Sci (Weinh) . 2025 May;12 (17) :e2413016.