FAPI-P8PN
FAPI-P8PN is a fibroblast activation protein (FAP) inhibitor (IC50=3.6 nM) . FAPI-P8PN is promising for research of FAP-overexpressing solid tumors[1].
Product Specifications
CAS Number
[2921619-09-0]
UNSPSC
12352005
Target
FAP
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
[O-]P(OCC(NCCCC[C@@H](C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(NC1=C2N=CC=C(C2=CC=C1)C(NCC(N3CC(F)(C[C@H]3C#N)F)=O)=O)=O)=O)NC(CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)(OCC[N+](C)(C)C)=O
Molecular Formula
C65H104F2N13O24P
Molecular Weight
1520.56
References & Citations
[1]Yuan H, et al. Structural Optimization of Fibroblast Activation Protein Inhibitors Through Zwitterionic and PEG Modification Strategy: Impact on Pharmacokinetics and Tumor Imaging. Mol Pharm. 2025 Aug 4;22 (8) :4831-4843.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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