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EGFR-IN-168

EGFR-IN-168 (Compound 9a) is a potent EGFR inhibitor with an IC50 of 0.069 μM. EGFR-IN-168 has antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

EGFR

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(/C=C/C1=CC=C(C=C1)F)C2=NC3=C(C=CC=C3)N2CC4=CN([C@@H]5[C@@H](O)[C@H](O)[C@H](O)[C@H](CO)O5)N=N4

Molecular Formula

C25H24FN5O6

Molecular Weight

509.49

References & Citations

[1]Srour AM, et al. New benzimidazole-triazole glycoconjugates as anti-cancer agents and EGFR inhibitors. Sci Rep. 2025 Jul 15;15 (1) :25514.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-175316/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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