DMU371
DMU371 is a Trypanosoma cruzi lysyl-tRNA synthetase 1 (KRS1) inhibitor (IC50=185 nM) . DMU371 is promising for research of infectious diseases[1].
Product Specifications
CAS Number
[3052352-34-5]
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
NC1=C2C(F)=C(F)C(NC3CCCC3)=C(F)C2=NC(C)=N1
Molecular Formula
C14H15F3N4
Molecular Weight
296.29
References & Citations
[1]Tulloch LB, et al. Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease. Sci Transl Med. 2025 Jul 9;17 (806) :eadu4564.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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