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RSK2-IN-5

RSK2-IN-5 (compoud C24) is a p90 ribosomal S6 kinase 2 (RSK2) inhibitor with a Kd of 317 ​nM. RSK2-IN-5 exhibits antitumor activity against breast cancer and melanoma cancer cells[1].

Product Specifications

CAS Number

[799832-19-2]

UNSPSC

12352005

Target

Ribosomal S6 Kinase (RSK)

Related Pathways

MAPK/ERK Pathway

Field of Research

Cancer

Purity

90.0

Smiles

O=C(C1=C(N)N(CC2=C(OC)C=CC=C2)C3=C1N=C4C=CC=CC4=N3)NC5CCCC5

Molecular Formula

C24H25N5O2

Molecular Weight

415.49

References & Citations

[1]Yue Zhao, et al. Discovery of novel p90 ribosomal S6 kinase 2 inhibitors for potential cancer treatment through ligand-based and structure-based virtual screening methods. Chemometrics and Intelligent Laboratory Systems. Volume 217, 15 October 2021, 104402

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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