CAIX-IN-4

CAIX-IN-4 (Compound 8b) is a selective carbonic anhydrase IX (CAIX) inhibitor with an IC50 value of 0.32 μM. CAIX-IN-4 is promising for research of cancers such as renal cell carcinoma[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C1C(C2=CSC(NC34C[C@H]5C[C@](C4)([H])C[C@@](C5)([H])C3)=N2)=CC6=C(O1)C=CC(Br)=C6

Molecular Formula

C22H21BrN2O2S

Molecular Weight

457.38

References & Citations

[1]Ahmed A, et al. Synthesis and evaluation of thiazolyl coumarin drug conjugates as carbonic anhydrase isozyme inhibitors by using integrated invitro and insilico approaches. Sci Rep. 2025 Jul 1;15 (1) :22032.