MC3935
MC3935 is a LSD1 inhibitor with an IC50 of 0.52 μM for LSD1-CoREST enzymatic complex. MC3935 has significant antischistosomal activity against transformed schistosomula (NTS) and Schistosoma mansoni adult worms while showing a delayed onset of action towards juvenile forms. MC3935 has no significant toxicity to human cells. MC3935 can be used for schistosomiasis research[1].
Product Specifications
UNSPSC
12352300
Target
Histone Demethylase
Related Pathways
Epigenetics
Field of Research
Infection
Smiles
O=C(NC1=CC=C(C2C(N)C2)C=C1)C3=CC=C(C#C)C=C3.Cl
Molecular Formula
C18H17ClN2O
Molecular Weight
312.79
References & Citations
[1]Fabbrizi E, et al. Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of Schistosoma mansoni. ACS Infect Dis. 2025 Jul 2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1
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