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NM600

NM600 is an alkylphosphocholine mimetic RPT agent. NM600 demonstrates an antitumor activity against a second GD2+ neuroblastoma xenograft model with SY5Y cells. NM600 can enhance suboptimal CAR T cell efficacy against solid tumors. NM600 can be studied in research for neuroblastoma[1].

Product Specifications

CAS Number

[2097522-37-5]

UNSPSC

12352128

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Smiles

O=P(OCC[N+](C)(C)C)([O-])OCCCCCCCCCCCCCCCCCCC1=CC=C(NC(CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2)=O)C=C1

Molecular Formula

C45H81N6O11P

Molecular Weight

913.13

References & Citations

[1] Sodji QH, et al., Low-dose radiation by radiopharmaceutical therapy enhances GD2 TRAC-CAR T cell efficacy in localized neuroblastoma. Sci Adv. 2025 Jun 6;11 (23) :eadu4417.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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