CD39-IN-1
CD39-IN-1 (Compound 338) is a selective small-molecule CD39 inhibitor with an IC50 value of 68.7 nM. CD39-IN-1 shows anti-proliferative activity on tumor cells. CD39-IN-1 blocks CD39-mediated eATP hydrolysis in the ATP-adenosine pathway. CD39-IN-1 is promising for research of cancers[1].
Product Specifications
UNSPSC
12352005
Target
NTPDase
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1C(C(NC2=CC=C(F)C(C(NC)=O)=C2C3=CN=C(OC4=CC=CC=C4)C=C3)=O)=CC5=CC=CC=C51
Molecular Formula
C29H23FN4O3
Molecular Weight
494.52
References & Citations
[1]Wang S, et al. Discovery of a novel CD39 inhibitor by DNA-encoded library screening. Bioorg Med Chem Lett. 2025 Jun 2;127:130294.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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