MCC-AAQ-Exa

MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs) . MCC is an ADC linker containing a maleimide fragment[1].

Product Specifications

CAS Number

[3052836-65-1]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

95.33

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1CCC(CC1)CN2C(C=CC2=O)=O)N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O

Molecular Formula

C47H53FN8O11

Molecular Weight

924.97

References & Citations

[1]Li Hongfeng, et al. Linker drug, and preparation method and use of antibody-drug conjugate thereof. World Intellectual Property Organization, WO2024160176 A1. 2024-08-08.