AR493
AR493 is an autophagy activator acting on AMPK (adenosine monophosphate-activated protein kinase) . AR493 regulates pathways related to cellular energy sensing and increases autophagy levels. AR493 is promising for research of aging-associated diseases (such as diabetes, neurodegenerative diseases) and autophagy regulation[1].
Product Specifications
CAS Number
[1290546-06-3]
UNSPSC
12352005
Target
AMPK; Autophagy
Related Pathways
Autophagy; Epigenetics; PI3K/Akt/mTOR
Field of Research
Metabolic Disease; Neurological Disease
Smiles
CN(C1=CC=CC=C1OC2=CN3[C@H]4C[C@H](O)[C@@H](CO)O4)C2=NC3=O
Molecular Formula
C16H17N3O5
Molecular Weight
331.32
References & Citations
[1]Guseva EA, et al. AMPK-specific autophagy activator based on 1,3-diaza-2-oxophenoxazine. Bioorg Chem. 2025 Jul 15;162:108588.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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