DT-23
DT-23 is a potent antifungal agent with an MIC50 of 15 μg/mL. DT-23 inhibits recombinant Arg1 and Kcs1 with IC50s of 0.6 and 0.68 μM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Fungal
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
FC(F)(F)C1=CC=CC(CNC2=NC(NC(CC3)CCN3CC4=CC=CC=C4)=C5C(NC=N5)=N2)=C1
Molecular Formula
C25H26F3N7
Molecular Weight
481.52
References & Citations
[1]Desmarini D, et al. Synthesis of a New Purine Analogue Class with Antifungal Activity and Improved Potency against Fungal IP3-4K. ACS Infect Dis. 2025 Apr 11;11 (4) :940-953.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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