SP-C01
SP-C01 is an orally active soluble epoxide hydrolase (sEH) inhibitor and partial PPARγ agonist. SP-C01 can inhibit Ser273 phosphorylation[1].
Product Specifications
CAS Number
[2982533-42-4]
UNSPSC
12352005
Target
Epoxide Hydrolase; PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
CC(OC1=CC=C(O[C@H]2CC[C@@H](CC2)NC(NC3=CC=C(C(F)=C3)OC(F)(F)F)=O)C=C1)=O
Molecular Formula
C22H22F4N2O5
Molecular Weight
470.41
References & Citations
[1]Cao R, et al. Structure-Based Design and Optimization Lead to the Identification of a Novel Potent sEH Inhibitor with PPARγ Partial Agonist Activity against Inflammatory and Metabolic-Related Diseases. J Med Chem. 2025 Apr 24;68 (8) :8729-8767.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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