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Insecticidal agent 21

Insecticidal agent 21 (Compound 6) is an insecticide that is effective against Culex pipiens larvae (LC50: 0.4 μg/mL) . Insecticidal agent 21 achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors (nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR) ) . Insecticidal agent 21 has a strong insecticidal effect and can be used in the development of new insecticides to address the problem of mosquito resistance to traditional insecticides[1].

Product Specifications

CAS Number

[3082443-45-3]

UNSPSC

12352005

Target

Cholinesterase (ChE) ; GABA Receptor; Insecticide; nAChR; Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Smiles

CCCCCCCCCCCC(NN1C(/C(C=C1C2=CC=C(C)C=C2)=C/C3=CC4=CC=C5C(C=CC=C5)=C4N=C3Cl)=O)=O

Molecular Formula

C37H40ClN3O2

Molecular Weight

594.19

References & Citations

[1]El-Helw EAE, et al. Synthesis of Benzo[h]quinoline derivatives and evaluation of their insecticidal activity against Culex pipiens L. larvae. Eur J Med Chem. 2025 Jun 5;290:117565.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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