PLA2-IN-1
PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A2 (PLA2) with an IC50 value of 1 nM PLA2-IN-1 inhibits PLA2-induced coagulopathy in vitro. PLA2-IN-1 is promising for research of snakebite envenomation caused by cobra venom[1].
Product Specifications
UNSPSC
12352100
Target
Phospholipase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(C1=CSC(NC(C(C2=CC=C(CC(C)C)C=C2)C)=O)=N1)OCC
Molecular Formula
C19H24N2O3S
Molecular Weight
360.47
References & Citations
[1]Nayyab BF, et al. Design, synthesis, and molecular docking studies of thiazole derivatives against phospholipase A2 (Naja oxiana) venom. Future Med Chem. 2025 Mar;17 (6) :659-667.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A
Curated Selection
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