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PLA2-IN-1

PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A2 (PLA2) with an IC50 value of 1 nM PLA2-IN-1 inhibits PLA2-induced coagulopathy in vitro. PLA2-IN-1 is promising for research of snakebite envenomation caused by cobra venom[1].

Product Specifications

UNSPSC

12352100

Target

Phospholipase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=C(C1=CSC(NC(C(C2=CC=C(CC(C)C)C=C2)C)=O)=N1)OCC

Molecular Formula

C19H24N2O3S

Molecular Weight

360.47

References & Citations

[1]Nayyab BF, et al. Design, synthesis, and molecular docking studies of thiazole derivatives against phospholipase A2 (Naja oxiana) venom. Future Med Chem. 2025 Mar;17 (6) :659-667.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Phospholipase A

Curated Selection

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