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Anti-MRSA agent 25

Anti-MRSA agent 25 (Compound 10c) is an antibacterial agent with a MIC of 0.25 μg/mL against methicillin-resistant Staphylococcus aureus (MRSA) . Anti-MRSA agent 25 exerts its antibacterial activity by inhibiting biofilm formation, disrupting the cell wall (interacting with peptidoglycan and lipoteichoic acids), acting on the cell membrane (causing depolarization, increasing permeability, and disrupting integrity), reducing metabolic activity, interfering with cellular redox homeostasis, and binding to DNA. Anti-MRSA agent 25 is expected to be used in the research of the anti-infection field[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

C[N+](C=C1)=CC2=C1C3=CC=CC=C3N2CCCCCCCCCCCN4C(C=CC=C5)=C5C6=C4C=[N+](C)C=C6.[I-].[I-]

Molecular Formula

C35H42I2N4

Molecular Weight

772.54

References & Citations

[1]Dan W, et al. Synthesis and anti-MRSA activity of quaternized small molecule antimicrobial peptide mimics based on norharmane. Eur J Med Chem. 2025 Jun 5;290:117518.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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